Incidence of Dravet Syndrome in a US Population
نویسندگان
چکیده
Investigators from the University of California, San Francisco and Kaiser Permanente report the incidence of Dravet Syndrome in a population based cohort.
منابع مشابه
Incidence of Dravet Syndrome in a US Population
OBJECTIVE: De novo mutations of the gene sodium channel 1a (SCN1A) are the major cause of Dravet syndrome, an infantile epileptic encephalopathy. US incidence of DS has been estimated at 1 in 40 000, but no US epidemiologic studies have been performed since the advent of genetic testing. METHODS: In a retrospective, population-based cohort of all infants born at Kaiser Permanente Northern Calif...
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Commentary Sudden unexpected death in epilepsy (SUDEP) is a rare, fatal complication of epilepsy defined as sudden death in an individual with epilepsy, in the absence of an obvious cause of death (1). The cause of SUDEP is unknown; however, it is hypothesized that there may be a disruption in respiration, heart rhythm, or cerebral shutdown (1). The population incidence of SUDEP in individuals ...
متن کاملPrevalence of SCN1A-Related Dravet Syndrome among Children Reported with Seizures following Vaccination: A Population-Based Ten-Year Cohort Study
OBJECTIVES To determine the prevalence of Dravet syndrome, an epileptic encephalopathy caused by SCN1A-mutations, often with seizure onset after vaccination, among infants reported with seizures following vaccination. To determine differences in characteristics of reported seizures after vaccination in children with and without SCN1A-related Dravet syndrome. METHODS Data were reviewed of 1,26...
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عنوان ژورنال:
دوره 29 شماره
صفحات -
تاریخ انتشار 2015